Our lab recently carried out an in silico analysis of transcription factors (TFs) in three nematode species, namely C. elegans, C. briggsae and C. remanei. This work has been published in a leading genomics journal BMC Genomics and placed among “Highly Accessed” papers.
Our comparative study revealed that each nematode species contains approximately 1,000 TF genes, of which 70% are conserved, i.e., share one-to-one 3-way orthologs. Roughly 15% of all nematode TF genes are also shared with fruit fly Drosophila melanogaster and mouse.
The findings were highlighted on the McMaster Daily News website.