This section contains reviews/summaries/critiques of selected published research articles in broad areas of biology, including evolutionary biology, developmental biology, and genetics. Some of these evaluations are part of my F1000 reviews (see my F1000 profile here).
Our lab recently carried out an in silico analysis of transcription factors (TFs) in three nematode species, namely C. elegans, C. briggsae and C. remanei. This work has been published in a leading genomics journal BMC Genomics and placed among “Highly Accessed” papers.
Our comparative study revealed that each nematode species contains approximately 1,000 TF genes, of which 70% are conserved, i.e., share one-to-one 3-way orthologs. Roughly 15% of all nematode TF genes are also shared with fruit fly Drosophila melanogaster and mouse.
The findings were highlighted on the McMaster Daily News website.